CPC A61K 47/55 (2017.08) | 5 Claims |
1. A compound of formula (I):
P—L—U (I)
or a pharmaceutically acceptable salt thereof, wherein
P is a FOXO1 fusion protein binding moiety and is:
L is a bivalent linker and is
and
U is an ubiquitin ligase binding moiety and is Cereblon (CRBN) E3 ligase moiety having the structure:
((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl) amino).
|