CPC A61K 36/87 (2013.01) [A23L 33/105 (2016.08); A61K 8/9789 (2017.08); A61Q 19/00 (2013.01); C14C 3/00 (2013.01); C14C 3/08 (2013.01); C14C 3/12 (2013.01); A61K 2800/10 (2013.01); A61K 2800/43 (2013.01); A61K 2800/522 (2013.01)] | 15 Claims |
1. A tannin extract obtained by a method comprising:
(a) adding an aqueous solution of a polyphenol-solubilizing agent to whole grape seeds without grinding or milling, wherein the polyphenol-solubilizing agent is selected from the group consisting of urea, sodium hydroxide, and a compound containing an SO3 group and is present at a concentration in the aqueous solution of 1-15% by weight with respect to the weight of the whole grape seeds;
(b) reacting the aqueous solution of the polyphenol-solubilizing agent and the whole grape seeds at a pressure ranging between 2.5 and 3.5 atmospheres, and a temperature ranging between 100° C. and 160° C., in a period of time ranging from 1-2 hours in an autoclave reactor; and
(c) recovering a liquid extract from the autoclave reactor,
wherein the liquid extract comprises a mixture of pure hydrolysable tannins, pure condensed tannins that include procyanidins, and non-tannins that include gallic acid, and further wherein the liquid extract has a content of tannins or polyphenols that is greater than 50%.
|