US 11,945,843 B2
Control of coleopteran pests using RNA molecules
Kevin L. Donohue, Research Triangle Park, NC (US); Yann Naudet, Ghent (BE); Pascale Feldmann, Ghent (BE); Lies Degrave, Ghent (BE); and Isabelle Maillet, Ghent (BE)
Assigned to SYNGENTA PARTICIPATIONS AG, Basel (CH)
Appl. No. 16/321,904
Filed by Syngenta Participations AG, Basel (CH)
PCT Filed Aug. 1, 2017, PCT No. PCT/US2017/044825
§ 371(c)(1), (2) Date Jan. 30, 2019,
PCT Pub. No. WO2018/026770, PCT Pub. Date Feb. 8, 2018.
Claims priority of provisional application 62/371,259, filed on Aug. 5, 2016.
Prior Publication US 2019/0185526 A1, Jun. 20, 2019
Int. Cl. C07K 14/42 (2006.01); C07K 14/325 (2006.01); C07K 16/18 (2006.01); C12N 9/42 (2006.01); C12N 15/82 (2006.01)
CPC C07K 14/42 (2013.01) [C07K 14/325 (2013.01); C07K 16/18 (2013.01); C12N 9/2442 (2013.01); C12N 15/8218 (2013.01); C12N 15/8286 (2013.01); C12Y 302/01014 (2013.01); Y02A 40/146 (2018.01)] 21 Claims
 
1. An interfering RNA molecule comprising a double-stranded RNA (dsRNA), the dsRNA consisting of annealed complementary strands, one strand of which consists of the nucleotide sequence of SEQ ID NO:390, and the other strand of which consists of the complement of SEQ ID NO:390, wherein the dsRNA has insecticidal activity on a coleopteran plant pest.