US 11,945,773 B2
Method for producing propionic acid derivative
Atsushi Shirai, Osaka (JP); Asako Yoshiyama, Osaka (JP); Makoto Matsuura, Osaka (JP); and Yoshichika Kuroki, Osaka (JP)
Assigned to DAIKIN INDUSTRIES, LTD., Osaka (JP)
Filed by DAIKIN INDUSTRIES, LTD., Osaka (JP)
Filed on Mar. 18, 2022, as Appl. No. 17/698,252.
Application 17/698,252 is a continuation of application No. PCT/JP2020/036909, filed on Sep. 29, 2020.
Claims priority of application No. 2019-179617 (JP), filed on Sep. 30, 2019; and application No. 2020-000399 (JP), filed on Jan. 6, 2020.
Prior Publication US 2022/0259132 A1, Aug. 18, 2022
Int. Cl. C07C 51/31 (2006.01); B01D 39/06 (2006.01); C07C 51/47 (2006.01)
CPC C07C 51/31 (2013.01) [B01D 39/06 (2013.01); C07C 51/47 (2013.01); B01D 2239/1241 (2013.01); B01D 2239/125 (2013.01)] 18 Claims
OG exemplary drawing
 
1. A method for producing a compound represented by formula (1):

OG Complex Work Unit Chemistry
wherein
R1 is a chlorine atom, a bromine atom, an iodine atom, or SR, wherein R is a hydrogen atom or a hydrocarbon group,
R2 and R3 are hydrogen atoms,
X is an oxygen atom,
R4 and R5 are fluorine atoms,
R6 is a C1-6 alkyl group, a haloalkyl group, or an aryl group;
the method comprising
step A of reacting a compound represented by formula (2):

OG Complex Work Unit Chemistry
wherein
R2 to R5 are as defined above, with a compound represented by formula (3):
M(R1)n  (3),
wherein
M is cation, n is an integer corresponding to the valence of M, and R1 is as defined above, and a compound represented by formula (4):
R6—X—H  (4),
wherein
R6 and X are as defined above;
step B of separating, by filtration, a compound represented by formula (5):
MFn  (5),
wherein
M and n are as defined above,
from the a mixture obtained by the above reaction; and
step C of performing a liquid separation treatment on a filtrate obtained by the filtration.