US 11,944,844 B2
Internal body cavity therapeutic applicators and methods for using them
Gary Lamoureux, Woodbury, CT (US); Juan-Carlos Diaz, Pembroke, FL (US); and Gil'ad Cohen, Tenafly, NJ (US)
Filed by Gary Lamoureux, Woodbury, CT (US); Juan-Carlos Diaz, Pembroke, FL (US); and Gil'ad Cohen, Tenafly, NJ (US)
Filed on Aug. 30, 2022, as Appl. No. 17/823,248.
Application 17/823,248 is a continuation of application No. 15/300,674, granted, now 11,446,515, previously published as PCT/US2015/023569, filed on Mar. 31, 2015.
Claims priority of provisional application 61/974,307, filed on Apr. 2, 2014.
Prior Publication US 2022/0409926 A1, Dec. 29, 2022
Int. Cl. A61N 5/10 (2006.01)
CPC A61N 5/10 (2013.01) [A61N 5/1002 (2013.01); A61N 5/1007 (2013.01); A61N 5/1014 (2013.01); A61N 2005/1003 (2013.01)] 20 Claims
OG exemplary drawing
 
1. An apparatus for providing radiation treatment to an anatomical lumen comprising muscular tissue, comprising:
an elongated member having the general configuration of a tube formed by a tubular sidewall and having a girth, a proximal end and a distal end, said elongated member defining an internal shaft surrounded by said tubular sidewall, and said elongated member comprising a proximal portion adjacent said proximal end and a distal portion adjacent said distal end;
at least one distal balloon inflation lumen, said at least one distal balloon inflation lumen defined within said tubular sidewall of said elongated member;
at least one proximal balloon inflation lumen, said at least one proximal balloon inflation lumen being positioned within said tubular sidewall of said elongated member;
at least one distal balloon mounted on said distal portion of said elongated member, said at least one distal balloon being inflatable to a size which fills a substantial portion of said anatomical lumen comprising muscular tissue, said at least one distal balloon being inflatable to a girth larger than the girth of said elongated member, said at least one distal balloon being positioned to be placed proximate healthy tissue portions of said anatomical lumen, said at least one distal balloon being in fluidic communication with said at least one distal balloon inflation lumen;
at least one valved distal balloon inflation coupling tube;
at least one proximal balloon mounted on said proximal portion of said elongated member, said at least one distal balloon being positioned between said at least one proximal balloon and said distal end of said elongated member, said at least one proximal balloon being inflatable to a size which fills a substantial portion of said anatomical lumen comprising muscular tissue, said at least one proximal balloon being inflatable to a girth larger than the girth of said elongated member, said at least one proximal balloon being positioned to be placed proximate other healthy tissue portions of said anatomical lumen, said at least one proximal balloon being in fluidic communication with said at least one proximal balloon inflation lumen;
at least one valved proximal balloon inflation coupling tube;
an intermediate region positioned between said at least one distal balloon and said at least one proximal balloon, said intermediate region being positioned to be placed proximate tumorous tissue portions of said anatomical lumen, wherein the anatomical lumen is selected from the group consisting of the esophagus, the rectum, the large intestine, the cardia and the small intestine; and
a source lumen adapted and configured to receive a radiation source, the source lumen positioned within said intermediate region;
wherein the intermediate region has a girth smaller than the girth to which said at least one proximal balloon and said at least one distal balloons may be inflated, whereby the girths of said at least one proximal balloon, the intermediate region and said at least one distal balloon cause the anatomical lumen to take a shape where healthy tissue is further displaced from the source lumen as compared to the displacement with respect to the source lumen of tumorous tissue adjacent the intermediate region of the elongated member, and tumorous tissue is positioned closer to said source lumen;
an input coupling member formed separately from and secured to said elongated member for coupling fluidic pressure to said at least one proximal balloon inflation lumen and said at least one distal balloon inflation lumens, said input coupling member defining coupler inputs for receiving at least one respective valved distal balloon inflation coupling tube and respective coupler outputs for coupling to at least one respective balloon inflation lumen, each coupler input and its respective coupler output being positioned at the input and the output of a respective coupler lumen defined in said input coupling member, said coupler lumens each having a non-straight configuration; and
wherein said input coupling member comprises:
(i) a hub insert; and
(ii) a hub outer body, said hub insert being positioned within said hub outer body.