US 11,940,765 B2
Intelligent closed-loop feedback control for transcranial stimulation
Brandon M Sepe, Medfield, MA (US); Raymond B Sepe, Jr., Medfield, MA (US); and Steven P Bastien, Exeter, RI (US)
Assigned to Electro Standards Laboratories, Cranston, RI (US)
Filed by ELECTRO STANDARDS LABORATORIES, Cranston, RI (US)
Filed on Apr. 16, 2020, as Appl. No. 16/851,051.
Prior Publication US 2021/0325836 A1, Oct. 21, 2021
Int. Cl. A61N 1/00 (2006.01); A61B 5/00 (2006.01); A61B 5/374 (2021.01); A61N 1/20 (2006.01); A61N 1/36 (2006.01); G05B 13/02 (2006.01); G06F 17/18 (2006.01); G06N 7/02 (2006.01); G16H 20/30 (2018.01); G16H 20/70 (2018.01)
CPC G05B 13/0295 (2013.01) [A61B 5/374 (2021.01); A61B 5/7217 (2013.01); A61B 5/7264 (2013.01); A61N 1/20 (2013.01); A61N 1/36031 (2017.08); G06F 17/18 (2013.01); G06N 7/02 (2013.01); G16H 20/30 (2018.01); G16H 20/70 (2018.01)] 25 Claims
OG exemplary drawing
 
1. A closed loop controller comprising:
a. a signal processing and statistics subsystem sampling an input data stream from at least one sensor, calculating real-time continuous statistics in the input data stream based on a sliding window technique, and outputting one or more classifications based on the real-time continuous statistics; and
b. an intelligent fuzzy logic controller receiving the one or more classifications from the signal processing and statistics subsystem, accessing a heuristic rule set based on expert knowledge, and outputting a noninvasive stimulation pattern based on the one or more classifications and the heuristic rule set.