US 11,940,451 B2
Microfluidic image analysis system
Vitaly Dobromyslin, Bedford, MA (US); and Shankar Balasubramanian, Bedford, MA (US)
Assigned to Instrumentation Laboratory Co., Bedford, MA (US)
Filed by Instrumentation Laboratory Co., Bedford, MA (US)
Filed on Dec. 20, 2021, as Appl. No. 17/555,939.
Prior Publication US 2023/0194555 A1, Jun. 22, 2023
Int. Cl. G01N 33/72 (2006.01); B01L 3/00 (2006.01); G06T 7/00 (2017.01)
CPC G01N 33/726 (2013.01) [B01L 3/502715 (2013.01); G06T 7/0012 (2013.01); G06T 7/97 (2017.01); B01L 2300/0663 (2013.01); G06T 2207/30072 (2013.01); G06T 2207/30168 (2013.01)] 20 Claims
OG exemplary drawing
 
1. A computer-implemented method comprising:
obtaining an image of a fluid of a microfluidic analysis system, wherein the microfluidic analysis system comprises or receives a container that contains the fluid for measurement of analyte or quality determination, and the image is captured using an imaging device associated with the microfluidic analysis system;
identifying, based on the image, a region of interest (ROI), wherein the ROI is a set of pixel values for use in the measurement of the analyte or the quality determination of the fluid, fluidic path, or measuring system and wherein identifying the ROI comprises
determining an alignment of the container of the fluid with the imaging device based on the image, and
identifying the ROI based on information about the measurement of the fluid or based on information about non-analyte features of the fluid; and
performing an analysis of the image of the fluid using the set of pixel values of the ROI.