US 11,940,428 B2
Preparative liquid chromatograph
Soichiro Tamaoki, Kyoto (JP); Tomoyuki Yamazaki, Kyoto (JP); and Shohei Sato, Kyoto (JP)
Assigned to SHIMADZU CORPORATION, Kyoto (JP)
Filed by SHIMADZU CORPORATION, Kyoto (JP)
Filed on Feb. 25, 2022, as Appl. No. 17/680,383.
Claims priority of application No. 2021-044357 (JP), filed on Mar. 18, 2021.
Prior Publication US 2022/0299488 A1, Sep. 22, 2022
Int. Cl. G01N 30/86 (2006.01); G01N 30/16 (2006.01); G01N 30/80 (2006.01); G01N 30/02 (2006.01)
CPC G01N 30/8651 (2013.01) [G01N 30/16 (2013.01); G01N 30/80 (2013.01); G01N 2030/027 (2013.01)] 4 Claims
OG exemplary drawing
 
1. A preparative liquid chromatograph comprising:
an analysis channel through which a mobile phase flows;
an injector that injects a sample into the mobile phase;
a separation column provided downstream of the injector on the analysis channel for separating components in the sample injected into the mobile phase;
a detector for detecting peaks of the components separated by the separation column;
a plurality of fraction collectors configured to fractionate the peaks detected by the detector at a downstream of the detector and to collect the peaks into collection containers respectively;
a switching valve that is interposed between an outlet of the detector and the plurality of fraction collectors and switches fraction collectors to be connected to the outlet of the detector among the plurality of fraction collectors; and
a controller for controlling operations of the plurality of fraction collectors and the switching valve,
wherein in response to a number of remaining unused collection containers of a fraction collector in use, which is connected to the outlet of the detector, falling below a predetermined number which is an integer of two or more, the controller is configured to switch the switching valve while the fraction collector in use is not performing a peak collection operation.