US 11,940,403 B2
Food allergen detection device and methods of use thereof
Srikanth Rao Agnihotra, Tyngsboro, MA (US); Madanodaya Sundhoro, Lowell, MA (US); Brent Amberger, Dracut, MA (US); Abigail Barnes, Madison, WI (US); Joseph Belbruno, Hanover, NH (US); Seung Hyuk Noh, Providence, RI (US); Jeanette Numbers, Providence, RI (US); and Elizabeth Soucy, Seattle, WA (US)
Assigned to Amulet, Inc., Madison, WI (US)
Appl. No. 16/609,943
Filed by Amulet, Inc., Madison, WI (US)
PCT Filed May 1, 2018, PCT No. PCT/US2018/030494
§ 371(c)(1), (2) Date Oct. 31, 2019,
PCT Pub. No. WO2018/204390, PCT Pub. Date Nov. 8, 2018.
Claims priority of provisional application 62/500,412, filed on May 2, 2017.
Prior Publication US 2020/0200694 A1, Jun. 25, 2020
Int. Cl. G01N 27/12 (2006.01); G01N 27/04 (2006.01); G01N 33/02 (2006.01); G01N 33/68 (2006.01); C08K 3/04 (2006.01)
CPC G01N 27/126 (2013.01) [G01N 27/045 (2013.01); C08K 3/041 (2017.05); C08K 2201/001 (2013.01); G01N 33/02 (2013.01); G01N 33/68 (2013.01); G01N 2600/00 (2013.01)] 18 Claims
OG exemplary drawing
 
1. A device comprising: a food allergen detection platform comprising:
a substrate;
a molecularly imprinted polymer layer in contact with the substrate, the molecularly imprinted polymer layer comprising receptor sites imprinted in a first surface of a polymer, the receptor sites configured to accept a trace molecule of a food allergen;
a non-imprinted polymer layer in contact with the substrate, wherein the non-imprinted polymer layer comprises the polymer which is not imprinted with receptor sites;
a sensor chip comprising the molecularly imprinted polymer and the non-imprinted polymer, which is configured to detect the presence of the trace molecule upon binding to one or more of the receptor sites on the molecularly imprinted polymer; and
a recess configured to house the sensor chip wherein the recess has a first portion for housing the sensor chip in a first position and a second portion for housing the sensor chip in a second position, the first and the second portions being linked such that the sensor chip is moveable from the first position to the second position in the recess.