US 11,940,369 B2
Multi-modal fluorescence imaging flow cytometry system
Eric D. Diebold, Menlo Park, CA (US); Keegan Owsley, Campbell, CA (US); and Jonathan Lin, San Gabriel, CA (US)
Assigned to BECTON, DICKINSON AND COMPANY, Franklin Lakes, NJ (US)
Filed by BECTON, DICKINSON AND COMPANY, Franklin Lakes, NJ (US)
Filed on Jun. 26, 2023, as Appl. No. 18/214,317.
Application 18/214,317 is a continuation of application No. 18/198,478, filed on May 17, 2023.
Application 18/198,478 is a continuation of application No. 17/745,249, filed on May 16, 2022, granted, now 11,692,926, issued on Jul. 4, 2023.
Application 17/745,249 is a continuation of application No. 17/153,527, filed on Jan. 20, 2021, granted, now 11,366,052, issued on Jun. 21, 2022.
Application 17/153,527 is a continuation of application No. 16/859,003, filed on Apr. 27, 2020, granted, now 10,935,482, issued on Mar. 2, 2021.
Application 16/859,003 is a continuation of application No. 16/299,001, filed on Mar. 11, 2019, granted, now 10,684,211, issued on Jun. 16, 2020.
Application 16/299,001 is a continuation of application No. 16/058,734, filed on Aug. 8, 2018, granted, now 10,288,546, issued on May 14, 2019.
Application 16/058,734 is a continuation of application No. 15/292,582, filed on Oct. 13, 2016, granted, now 10,078,045, issued on Sep. 18, 2018.
Claims priority of provisional application 62/240,894, filed on Oct. 13, 2015.
Prior Publication US 2023/0333002 A1, Oct. 19, 2023
Int. Cl. G01N 15/14 (2006.01); G01N 21/64 (2006.01); G02B 21/06 (2006.01); G01N 15/10 (2006.01)
CPC G01N 15/1434 (2013.01) [G01N 15/14 (2013.01); G01N 15/1425 (2013.01); G01N 15/1429 (2013.01); G01N 15/147 (2013.01); G01N 15/1475 (2013.01); G01N 21/645 (2013.01); G02B 21/06 (2013.01); G01N 2015/1006 (2013.01); G01N 2015/1447 (2013.01); G01N 2015/1454 (2013.01); G01N 2021/6482 (2013.01)] 17 Claims
OG exemplary drawing
 
1. A system comprising:
a flow cell comprising a flow channel for propagating a sample therethrough comprising particles in a flow stream;
a light beam generator component comprising:
a single acousto-optic device; and
a laser configured to irradiate the acousto-optic device to generate a frequency shifted beam of light; and
a light detection system comprising a photodetector configured to detect light from an irradiated particle in the sample and generate data signals in response to the detected light that has image information encoded in the time domain.