	US 11,939,576 B2
	Transgenic microalgae and use thereof as a feed for delivery of interfering RNA molecules
Ofra Chen, Rehovot (IL)
Assigned to TRANSALGAE ISRAEL LTD., Rehovot (IL)
Filed by TRANSALGAE ISRAEL LTD., Rehovot (IL)
Filed on Aug. 26, 2020, as Appl. No. 17/003,254.
Application 17/003,254 is a continuation of application No. 15/741,898, granted, now 10,781,447, previously published as PCT/IL2016/050760, filed on Jul. 14, 2016.
Claims priority of provisional application 62/192,082, filed on Jul. 14, 2015.
Prior Publication US 2021/0032625 A1, Feb. 4, 2021
This patent is subject to a terminal disclaimer.
Int. Cl. C12N 15/113 (2010.01); A01N 65/00 (2009.01); A01N 65/03 (2009.01); A23K 10/16 (2016.01); A23K 20/00 (2016.01); A23K 20/153 (2016.01); A23K 50/10 (2016.01); A23K 50/80 (2016.01); A23L 17/60 (2016.01); A61K 31/713 (2006.01); A61K 36/02 (2006.01); C12N 1/12 (2006.01); C12N 15/11 (2006.01); C12N 15/82 (2006.01)

CPC C12N 15/113 (2013.01) [A01N 65/00 (2013.01); A01N 65/03 (2013.01); A23K 10/16 (2016.05); A23K 20/00 (2016.05); A23K 20/153 (2016.05); A23K 50/10 (2016.05); A23K 50/80 (2016.05); A23L 17/60 (2016.08); A61K 31/713 (2013.01); A61K 36/02 (2013.01); C12N 1/12 (2013.01); C12N 15/111 (2013.01); C12N 15/1131 (2013.01); C12N 15/8286 (2013.01); C12N 2310/14 (2013.01); C12N 2320/32 (2013.01); Y02A 40/146 (2018.01)]

5 Claims

1. A non-propagating transgenic Phaeodactylum tricornutum microalga comprising at least one heterologous RNAi molecule, wherein the RNAi molecule is targeted to a clk gene present within an insect plant pest and wherein said RNAi molecule silences the expression of the clk gene present within the insect plant pest when the microalga is consumed by said insect plant pest, wherein said microalga is in a dried form.