	US 11,939,574 B2
	Ribosomal RNA origami and methods preparing thereof
Anastasia Shapiro, Rishon Lezion (IL); Ido Bachelet, Tel-Aviv (IL); Yaniv Amir, Yehud (IL); Erez Lavi, Bat Yam (IL); and Danielle Karo-Atar, Ramla (IL)
Assigned to AUGMANITY NANO LTD, Rehovot (IL)
Appl. No. 16/479,000
Filed by AUGMANITY NANO LTD, Rehovot (IL)
PCT Filed Jan. 18, 2018, PCT No. PCT/IL2018/050072 § 371(c)(1), (2) Date Jul. 18, 2019, PCT Pub. No. WO2018/134825, PCT Pub. Date Jul. 26, 2018.
Claims priority of application No. 250207 (IL), filed on Jan. 19, 2017.
Prior Publication US 2019/0352640 A1, Nov. 21, 2019
Int. Cl. C12N 15/11 (2006.01); C12N 15/10 (2006.01); C12N 15/115 (2010.01)

CPC C12N 15/11 (2013.01) [C12N 15/10 (2013.01); C12N 15/115 (2013.01); C12N 2310/16 (2013.01); C12N 2310/3513 (2013.01); C12N 2310/3519 (2013.01); C12N 2310/50 (2013.01); C12N 2310/53 (2013.01)]

17 Claims

1. An RNA origami nanostructure comprising one or more scaffold nucleic acid strands and a plurality of staple nucleic acid strands, wherein each one of the plurality of staple nucleic acid strands hybridizes with at least two non-contiguous sequences within said one or more scaffold nucleic acid strands, and wherein said one or more scaffold nucleic acid strands comprise a ribosomal RNA (rRNA) nucleic acid, a fragment thereof, or an analog thereof.