US 11,939,403 B2
Peptide-peptoid scaffolds
R. Lokey, Santa Cruz, CA (US); and Akihiro Furukawa, Tokyo (JP)
Assigned to The Regents of the University of California, Oakland, CA (US)
Filed by The Regents of the University of California, Oakland, CA (US)
Filed on Jul. 2, 2021, as Appl. No. 17/366,822.
Claims priority of provisional application 63/047,788, filed on Jul. 2, 2020.
Prior Publication US 2022/0002346 A1, Jan. 6, 2022
Int. Cl. C07K 7/54 (2006.01); C07K 7/64 (2006.01)
CPC C07K 7/54 (2013.01) 27 Claims
 
1. A compound of a structure

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wherein Za1 is X1 or methyl (CH3—),
wherein Za2 is X2 or methyl (CH3—),
wherein Za4 is H or 2-methylpropyl

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wherein Za5 is H or 2-methylpropyl

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wherein Zb1 is X1 or methyl (CH3—),
wherein Zb2 is X2 or methyl (CH3—),
wherein Zb4 is H or methyl (CH3—),
wherein Zb5 is H or methyl (CH3—),
wherein Zc1 is 2-methylpropyl

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or methyl (CH3—),
wherein Zc2 is 2-methylpropyl

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or methyl (CH3—),
wherein X1 is selected from the group consisting of ethyl (Et-)

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2-propoxy-3-propyl

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and (1,3-benzodioxol-5-yl)-methyl

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wherein X2 is selected from the group consisting of pentyl

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cyclohexylmethyl

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and (oxan-4-yl)methyl

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and
wherein X3 is selected from the group consisting of methyl

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and benzyl

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