US 11,939,357 B2
Modified meningococcal fHbp polypeptides
Matthew Bottomley, Siena (IT); and Vega Masignani, Siena (IT)
Assigned to GLAXOSMITHKLINE BIOLOGICALS SA, Rixensart (BE)
Filed by GLAXOSMITHKLINE BIOLOGICALS SA, Rixensart (BE)
Filed on Jun. 14, 2021, as Appl. No. 17/346,362.
Application 17/346,362 is a continuation of application No. 15/319,651, granted, now 11,066,450, previously published as PCT/EP2015/066228, filed on Jul. 16, 2015.
Claims priority of application No. 14177564 (EP), filed on Jul. 17, 2014.
Prior Publication US 2022/0002355 A1, Jan. 6, 2022
Int. Cl. C07K 14/22 (2006.01); A61K 39/00 (2006.01); A61K 39/095 (2006.01)
CPC C07K 14/22 (2013.01) [A61K 39/095 (2013.01); A61K 2039/575 (2013.01); C07K 2319/33 (2013.01)] 7 Claims
 
1. A polypeptide comprising an amino acid sequence having at least 90% sequence identity to SEQ ID NO: 17, wherein (a) the amino acid sequence differs from SEQ ID NO: 17 at residues 126 and 243 relative to SEQ ID NO:17.