US 11,939,353 B2
Fluorinated and alkylated bile acids
Michael Finch, Minneapolis, MN (US); Cyrus B. Munshi, Blaine, MN (US); Cecilia M. P. Rodrigues, Lisbon (PT); and Susana Dias Lucas de Oliveira, Sao Joao da Talha (PT)
Assigned to Metselex, inc., Minneapolis, MN (US)
Filed by Metselex, Inc., Minneapolis, MN (US)
Filed on Jul. 16, 2021, as Appl. No. 17/378,198.
Application 17/378,198 is a division of application No. 15/556,768, granted, now 11,072,630, previously published as PCT/US2016/021809, filed on Mar. 10, 2016.
Claims priority of provisional application 62/141,506, filed on Apr. 1, 2015.
Claims priority of provisional application 62/130,931, filed on Mar. 10, 2015.
Prior Publication US 2022/0002339 A1, Jan. 6, 2022
Int. Cl. A61K 31/025 (2006.01); C07J 9/00 (2006.01); C07J 41/00 (2006.01); C07J 51/00 (2006.01); C07J 63/00 (2006.01); B01J 37/26 (2006.01)
CPC C07J 9/005 (2013.01) [A61K 31/025 (2013.01); C07J 41/0061 (2013.01); C07J 51/00 (2013.01); C07J 63/008 (2013.01); B01J 37/26 (2013.01); C07C 2603/52 (2017.05)] 6 Claims
 
1. A compound selected from the following table:

OG Complex Work Unit Chemistry

OG Complex Work Unit Chemistry
wherein R1 is —OH, —O—(CH2)—O—P(O)(OH)2, —OP(O)(OH)2, or —F;
or a pharmaceutically acceptable salt thereof.