US 11,939,303 B2
Sulfamate derivatives of 4-(1-phenyl-1H-[1,2,3]triazol-4-yl)-phenol, derivatives of 4-(1-phenyl-1H-[1,2,3]triazol-4-yl)-phenol, their medical use and the method of obtaining 4-(1-phenyl-1H-[1,2,3]triazol-4-yl)-phenyl sulfamate derivatives
Sebastian Demkowicz, Gdansk (PL); Mateusz Dasko, Pruszcz Gdanski (PL); and Janusz Rachon, Gdansk (PL)
Assigned to Politechnika Gdanska, Gdansk (PL)
Appl. No. 17/252,703
Filed by POLITECHNIKA GDANSKA, Gdansk (PL)
PCT Filed Aug. 20, 2018, PCT No. PCT/PL2018/000080
§ 371(c)(1), (2) Date Dec. 15, 2020,
PCT Pub. No. WO2019/245393, PCT Pub. Date Dec. 26, 2019.
Claims priority of application No. 425970 (PL), filed on Jun. 18, 2018.
Prior Publication US 2021/0188785 A1, Jun. 24, 2021
Int. Cl. C07D 249/06 (2006.01); A61P 35/00 (2006.01); G01N 33/573 (2006.01); A61K 31/4192 (2006.01)
CPC C07D 249/06 (2013.01) [A61P 35/00 (2018.01); G01N 33/573 (2013.01); A61K 31/4192 (2013.01)] 10 Claims
 
1. Chemical compound that imitate the steroid system and contain a sulfamate moiety, the compound defined by the general formula 1:

OG Complex Work Unit Chemistry
wherein R1═H or F or CF3 or OCF3; R2═H or F or CF3 or Cl or Br or I or CH3 or OCH3 or Et or iPr or NO2; R3═H or F or CF3 or OCF3; R4═H or F or CF3 or Cl or Br or I or CH3 or OCH3; R5 ═H or F or CF3.