US 11,939,294 B1
1-(2-(substituted phenyl)-2-oxoethyl)-3,5-dimethylpyridin-1-ium bromides as antitubercular agents
Katharigatta N. Venugopala, Al-Ahsa (SA); Mahmoud Kandeel, Al-Ahsa (SA); Melendran Pillay, Durban (ZA); Osama I. Alwassil, Al-Ahsa (SA); Mohamed A. Morsy, Al-Ahsa (SA); Rashmi Venugopala, Al-Ahsa (SA); Sandeep Chandrashekharappa, Lucknow (IN); and Bandar E. Aldhubiab, Al-Ahsa (SA)
Assigned to KING FAISAL UNIVERSITY, Al-Ahsa (SA)
Filed by KING FAISAL UNIVERSITY, Al-Ahsa (SA)
Filed on Oct. 23, 2023, as Appl. No. 18/492,723.
Int. Cl. C07D 213/18 (2006.01); A61P 31/06 (2006.01)
CPC C07D 213/18 (2013.01) [A61P 31/06 (2018.01)] 8 Claims
 
1. A method of treating tuberculosis in a patient, comprising administering to a patient in need thereof a therapeutically effective amount of a compound having the formula I:

OG Complex Work Unit Chemistry
or a pharmaceutically acceptable salt, ester, stereoisomer, or solvate thereof, wherein: one or more R1 groups is attached to the phenyl ring, wherein each R1 is independently selected from the group consisting of trihalomethyl, methoxy, NO2, and a halogen.