CPC A61L 27/56 (2013.01) [A61F 2/06 (2013.01); A61F 2/07 (2013.01); A61L 27/52 (2013.01); A61L 27/54 (2013.01); A61L 27/58 (2013.01); A61L 31/10 (2013.01); A61L 31/16 (2013.01); A61F 2002/072 (2013.01); A61F 2002/077 (2013.01); A61F 2210/0061 (2013.01); A61L 2300/42 (2013.01)] | 22 Claims |
1. A method of delivering a hydrogel-associated endovascular prosthesis to a target blood vessel of a patient, the method comprising:
providing a hydrogel-associated endovascular prosthesis having a compressed configuration for delivery within a vasculature and a radially-expanded configuration for deployment within the target blood vessel, the prosthesis comprising:
an anchor stent for engaging an inner wall of the target blood vessel when the prosthesis is in the radially-expanded configuration;
a tubular body formed from a graft material defining a central lumen from a first end to a second end thereof, wherein the anchor stent is attached to the first end of the tubular body, the tubular body having an inner surface and an outer surface;
one or more body stents attached to the outer surface of the tubular body for maintaining the tubular body in the radially-expanded configuration; and
a hydrogel composition associated with only the outer surface of the graft material of the tubular body, wherein the hydrogel composition is in a non-expanded state and configured to swell to an expanded state following introduction into the target blood vessel of the patient and contact with blood;
introducing the hydrogel-associated endovascular prosthesis transluminally into a selected portion of the target blood vessel, wherein the hydrogel composition is in the non-expanded state prior to the introducing;
radially expanding the endovascular prosthesis into contact with the target blood vessel;
contacting the hydrogel composition with blood; and
swelling the hydrogel composition radially outward into the expanded state within the target blood vessel to fill in empty volume that surrounds the endovascular prosthesis.
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