US 11,938,231 B2
Compositions I-I and products and uses thereof
Marcus Damian Phillips, Heslington (GB)
Assigned to Smith & Nephew PLC, Watford (GB)
Filed by Smith & Nephew PLC, Watford (GB)
Filed on Nov. 9, 2020, as Appl. No. 17/093,214.
Application 17/093,214 is a division of application No. 16/213,630, filed on Dec. 7, 2018, abandoned.
Application 16/213,630 is a continuation of application No. 13/989,560, abandoned, previously published as PCT/GB2011/001649, filed on Nov. 25, 2011.
Claims priority of application No. 1020005 (GB), filed on Nov. 25, 2010.
Prior Publication US 2021/0121599 A1, Apr. 29, 2021
Int. Cl. A61L 15/42 (2006.01); A61L 15/26 (2006.01); A61L 15/58 (2006.01); A61L 24/00 (2006.01); A61L 26/00 (2006.01)
CPC A61L 15/425 (2013.01) [A61L 15/26 (2013.01); A61L 15/58 (2013.01); A61L 24/0073 (2013.01); A61L 26/0095 (2013.01)] 13 Claims
 
1. A method of preparing, the method comprising:
providing a curable composition apportioned between at least one Part A and at least one Part B, the composition comprising:
one or more alkenyl-containing prepolymers including at least one alkenyl moiety per molecule,
one or more SiH-containing prepolymers including at least one SiH unit per molecule,
a catalyst facilitating curing by addition of alkenyl-containing prepolymer to SiH-containing prepolymer, and
a blowing agent configured to evolve gas as part of or during a curing reaction,
wherein the Part A is sealed within a first receptacle and does not include the one or more SiH-containing prepolymers, and
wherein the Part B is sealed within a second receptacle and does not include the catalyst; and
heating the first receptacle containing Part A and the second receptacle containing Part B at an elevated temperature of 123° C. or higher for a period of 18 hours or longer, wherein the at least one Part A and the at least one Part B are terminally sterile and kept sealed within the first receptacle and the second receptacle without degrading or interacting with the first receptacle and the second receptacle, respectively, during or after heating.