US 11,938,230 B2
Hemostatic material and wound dressing containing same
Kazuhiko Shibata, Tokyo (JP)
Assigned to Artisan Lab Co., Ltd., Tokyo (JP); and NIPRO Corporation, Osaka (JP)
Filed by Artisan Lab Co., Ltd., Tokyo (JP); and NIPRO Corporation, Osaka (JP)
Filed on Aug. 9, 2022, as Appl. No. 17/818,551.
Application 17/818,551 is a continuation of application No. 16/634,304, abandoned, previously published as PCT/JP2017/027890, filed on Aug. 1, 2017.
Prior Publication US 2022/0378974 A1, Dec. 1, 2022
Int. Cl. A61L 15/28 (2006.01); A61L 15/44 (2006.01); C08B 15/06 (2006.01)
CPC A61L 15/28 (2013.01) [A61L 15/44 (2013.01); C08B 15/06 (2013.01); A61L 2300/418 (2013.01); A61L 2400/04 (2013.01)] 9 Claims
 
1. A method for stopping bleeding at a bleeding wound site, comprising applying cationized cellulose having water-holding property and hemostatic properties of absorbing and coagulating blood to the bleeding wound site to stop the bleeding at the wound site wherein the cationized cellulose is of formula (1):
wherein

OG Complex Work Unit Chemistry
(a) at least one R1 in the formula (1) represents −CH2CH2O—CH2CH(OH)CH2—N+(R3)(R4)(R5).X−, and R3, R4 and R5 are independently a methyl group or an ethyl group,
or
(b) at least one R1 in the formula (1) represents —CH2CH(OH)CH2N+(R3)(R4)(R5).X31 , and R3, R4 and R5 are independently a methyl group or an ethyl group
wherein X−represents an anionic group,
other R1 each represent —H, or —(CH2CH2O)m—H; where m is 1 or 2.