CPC A61K 9/0019 (2013.01) [A61K 9/08 (2013.01); A61K 31/27 (2013.01); A61K 31/40 (2013.01); A61K 47/183 (2013.01)] | 19 Claims |
1. A stable ready-to-use injectable pharmaceutical composition for reversing effects of non-depolarizing neuromuscular blocking agents in a patient in need thereof, comprising:
(i) about 1 mg/mL of neostigmine or a pharmaceutically acceptable salt, solvate or hydrate thereof,
(ii) about 0.2 mg/mL of glycopyrrolate or a pharmaceutically acceptable salt, solvate or hydrate thereof, and
(iii) a pharmaceutically acceptable liquid vehicle,
wherein the pharmaceutical composition has a pH ranging from 3.0 to 4.0, and
wherein said composition is stable when stored at 40° C. and 75% relative humidity for at least 3 months.
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