US 11,938,204 B2
Oil-in-water emulsions of which the oil phase is in the form of a mixture of drops of different sizes
Mathieu Goutayer, Saint Malo (FR); Yan Eric Pafumi, Gardanne (FR); Lucie Chatry, Chateauroux-les-Alpes (FR); and Hélène Balbusquier, Sainte-Radegonde (FR)
Assigned to CAPSUM, Marseilles (FR)
Appl. No. 16/077,049
Filed by CAPSUM, Marseilles (FR)
PCT Filed Feb. 10, 2017, PCT No. PCT/EP2017/053063
§ 371(c)(1), (2) Date Aug. 10, 2018,
PCT Pub. No. WO2017/137597, PCT Pub. Date Aug. 17, 2017.
Claims priority of application No. 1651172 (FR), filed on Feb. 12, 2016.
Prior Publication US 2021/0121375 A1, Apr. 29, 2021
Int. Cl. A61K 8/06 (2006.01); A61K 8/11 (2006.01); A61K 8/25 (2006.01); A61K 8/73 (2006.01); A61K 8/81 (2006.01); A61K 8/898 (2006.01); A61K 8/92 (2006.01); A61Q 17/04 (2006.01); A61Q 19/00 (2006.01); A61Q 19/08 (2006.01)
CPC A61K 8/062 (2013.01) [A61K 8/11 (2013.01); A61K 8/25 (2013.01); A61K 8/73 (2013.01); A61K 8/8152 (2013.01); A61K 8/898 (2013.01); A61K 8/922 (2013.01); A61Q 17/04 (2013.01); A61Q 19/007 (2013.01); A61Q 19/08 (2013.01); A61K 2800/41 (2013.01); A61K 2800/42 (2013.01); A61K 2800/594 (2013.01); A61K 2800/624 (2013.01)] 20 Claims
 
1. A composition in the form of an oil-in-water emulsion, comprising a continuous aqueous phase and a dispersed oil phase in the form of drops (G1) and (G2),
wherein the drops (G1) comprise an oil phase and a shell formed of at least one anionic polymer (PA1) and at least one cationic polymer (PC1), wherein the size of the drops (G1) is less than 500 μm,
wherein the drops (G2) comprise an oil phase and a shell, said shell being formed of at least one anionic polymer (PA2), identical to or different from (PA1), and at least one cationic polymer (PC2), identical or different from (PC1), wherein the size of the drops (G2) is greater than 500 μm,
wherein the drops (G1) and (G2) are different in nature, in regard to the nature of the anionic and cationic polymers, or oils and/or additional compounds and/or active agents
wherein the anionic polymers (PA1) and (PA2) are hydrophilic, and the cationic polymers (PC1) and (PC2) are liposoluble, and
wherein the composition does not include a surfactant.