US 11,938,197 B2
Polynucleotides and vectors for the expression of transgenes
Ian Alexander, Westmead (AU); and Sharon Cunningham, Westmead (AU)
Assigned to THE SYDNEY CHILDREN'S HOSPITALS NETWORK (RANDWICK AND WESTMEAD (INCORPORATING THE ROYAL ALEXANDRA HOSPITAL FOR CHILDREN), Westmead (AU); and CHILDREN'S MEDICAL RESEARCH INSTITUTE, Westmead (AU)
Appl. No. 16/477,168
Filed by Children's Medical Research Institute, Westmead (AU); and The Sydney Children's Hospitals Network (Randwick and Westmead) (incorporating The Royal Alexandra Hospital for Children), Westmead (AU)
PCT Filed Jan. 10, 2018, PCT No. PCT/AU2018/050011
§ 371(c)(1), (2) Date Jul. 10, 2019,
PCT Pub. No. WO2018/129586, PCT Pub. Date Jul. 19, 2018.
Claims priority of application No. 2017900050 (AU), filed on Jan. 10, 2017.
Prior Publication US 2019/0365926 A1, Dec. 5, 2019
Int. Cl. C12N 15/67 (2006.01); A61K 48/00 (2006.01); C12N 9/10 (2006.01); C12N 15/86 (2006.01)
CPC A61K 48/0058 (2013.01) [C12N 9/1018 (2013.01); C12N 15/67 (2013.01); C12N 15/86 (2013.01); C12N 2750/14143 (2013.01); C12N 2840/007 (2013.01); C12Y 201/03003 (2013.01)] 7 Claims
OG exemplary drawing
 
1. A polynucleotide comprising the sequence of SEQ ID NO: 17 or a sequence having at least or about 99% sequence identity thereto, wherein the polynucleotide can express a functional ornithine transcarbamylase (OTC) polypeptide.