	US 11,938,189 B2
	Compositions and methods for stabilizing protein-containing formulations
Osigwe Esue, San Mateo, CA (US); and Vikas K. Sharma, Millbrae, CA (US)
Assigned to Genentech, Inc, South San Francisco, CA (US)
Filed by Genentech, Inc., South San Francisco, CA (US)
Filed on Jul. 27, 2021, as Appl. No. 17/386,385.
Application 17/386,385 is a division of application No. 16/215,003, filed on Dec. 10, 2018, granted, now 11,103,584.
Application 16/215,003 is a division of application No. 14/966,363, filed on Dec. 11, 2015, granted, now 10,188,735, issued on Jan. 29, 2019.
Application 14/966,363 is a division of application No. 13/722,559, filed on Dec. 20, 2012, granted, now 9,254,321, issued on Feb. 9, 2016.
Application 13/722,559 is a continuation of application No. PCT/US2011/041598, filed on Jun. 23, 2011.
Claims priority of provisional application 61/358,105, filed on Jun. 24, 2010.
Prior Publication US 2021/0353756 A1, Nov. 18, 2021
This patent is subject to a terminal disclaimer.
Int. Cl. A61K 39/395 (2006.01); A61K 9/00 (2006.01); A61K 9/19 (2006.01); A61K 47/10 (2017.01); A61K 47/26 (2006.01); C07K 16/00 (2006.01); C07K 16/28 (2006.01); C07K 16/30 (2006.01)

CPC A61K 47/26 (2013.01) [A61K 9/0019 (2013.01); A61K 9/19 (2013.01); A61K 39/39591 (2013.01); A61K 47/10 (2013.01); C07K 16/00 (2013.01); C07K 16/2803 (2013.01); C07K 16/2845 (2013.01); C07K 16/3092 (2013.01); C07K 2317/76 (2013.01); C07K 2317/94 (2013.01)]

15 Claims

1. An aqueous composition comprising an antibody-toxin conjugate and an alkylglycoside having a CMC value of about 1.0 mM or greater in water at 25° C., wherein the alkylglycoside is present in the aqueous composition at a concentration that is lower than the CMC value of the alkylglycoside in water at 25° C.