US 11,938,129 B2
Methods and compositions for the treatment of vascular disease
Mark E. Lindsay, Winchester, MA (US); Christian Lacks Lino Cardenas, Boston, MA (US); and Rajeev Malhotra, Boston, MA (US)
Assigned to THE GENERAL HOSPITAL CORPORATION
Appl. No. 16/969,743
Filed by THE GENERAL HOSPITAL CORPORATION, Boston, MA (US)
PCT Filed Feb. 19, 2019, PCT No. PCT/US2019/018501
§ 371(c)(1), (2) Date Aug. 13, 2020,
PCT Pub. No. WO2019/161364, PCT Pub. Date Aug. 22, 2019.
Claims priority of provisional application 62/793,614, filed on Jan. 17, 2019.
Claims priority of provisional application 62/632,105, filed on Feb. 19, 2018.
Prior Publication US 2021/0038596 A1, Feb. 11, 2021
Int. Cl. A61K 31/496 (2006.01); A61K 31/4178 (2006.01); A61P 9/00 (2006.01)
CPC A61K 31/496 (2013.01) [A61K 31/4178 (2013.01); A61P 9/00 (2018.01)] 2 Claims
 
1. A method of treating a thoracic aortic aneurysm, the method comprising administering to a subject in need thereof a therapeutically effective dose of GSK343.