US 11,938,120 B1
Ethyl 2-substituted-1-(substitutedbenzoyl)-7-methylpyrrolo[1,2-a]quinoline-3-carboxylate derivatives as anti-tubercular agents
Katharigatta N. Venugopala, Al-Ahsa (SA); Pran Kishore Deb, Ranchi (IN); Melendran Pillay, Durban (ZA); Sandeep Chandrashekharappa, Lucknow (IN); Mohamed A. Morsy, Al-Ahsa (SA); Bandar Aldhubiab, Al-Ahsa (SA); Mahesh Attimarad, Al-Ahsa (SA); Anroop B. Nair, Al-Ahsa (SA); Nagaraja Sreeharsha, Al-Ahsa (SA); Christophe Tratrat, Al-Ahsa (SA); Sheena Shashikanth, Mysore (IN); Vijaykumar Uppar, Rani Channamma (IN); and Basavaraj Padmashali, Rani Channamma (IN)
Assigned to KING FAISAL UNIVERSITY, Al-Ahsa (SA)
Filed by KING FAISAL UNIVERSITY, Al-Ahsa (SA)
Filed on Aug. 23, 2023, as Appl. No. 18/237,273.
Int. Cl. A61K 31/4745 (2006.01); A61K 31/437 (2006.01); A61P 31/06 (2006.01)
CPC A61K 31/437 (2013.01) [A61P 31/06 (2018.01)] 16 Claims
 
1. A method of treating tuberculosis in a patient, comprising administering to a patient in need thereof a therapeutically effective amount of a compound having the formula I:

OG Complex Work Unit Chemistry
or a pharmaceutically acceptable salt, or stereoisomer thereof, wherein:
R is selected from the group consisting of methyl, hydrogen, fluorine, bromine, —NO2, and trifluoromethyl; and
n is 1 or 2.