| CPC A61B 5/0071 (2013.01) [A61B 5/0035 (2013.01); A61B 5/0044 (2013.01); A61B 5/0077 (2013.01); A61B 5/7203 (2013.01); G06T 5/70 (2024.01); G06T 7/0016 (2013.01); A61B 2562/0233 (2013.01); A61B 2576/023 (2013.01); G06T 2207/10016 (2013.01); G06T 2207/10024 (2013.01); G06T 2207/10048 (2013.01); G06T 2207/10064 (2013.01); G06T 2207/20182 (2013.01); G06T 2207/30048 (2013.01); G06T 2207/30096 (2013.01); G06T 2207/30101 (2013.01)] | 4 Claims |
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1. A time intensity curve measuring apparatus which measures a time intensity curve illustrating a temporal change in pixel value of light emission from a fluorescent dye administered into a body of a subject, the apparatus comprising:
an excitation ray source which emits near-infrared rays for exciting a fluorescent dye administered into the body of the subject toward the subject;
an image pickup unit including:
a first photographing element configured to detect near-infrared rays from the fluorescent dye, and obtain a fluorescence image of a tissue of the subject; and
a second photographing element configured to detect visible rays, and obtain a color image of the tissue of the subject; and
a wavelength selection filter configured to make visible rays and fluorescence incident coaxially split into visible rays and fluorescence such that the fluorescence is incident on the first photographing element and the visible rays are incident on the second photographing element,
the image pickup unit being configured to simultaneously detect near-infrared rays from the fluorescent dye and visible rays, and obtain a plurality of fluorescence images of the tissue of the subject and a plurality of color images of the tissue of the subject, wherein each of the plurality of fluorescence images is obtained by the first photographing element based on the detected near-infrared rays from the fluorescent dye and each of the plurality of color images is obtained by the second photographing element based on the detected visible rays, the plurality of fluorescence images include a first fluorescence image and a second fluorescence image, the plurality of color images include a first color image and a second color image, and the second fluorescence image and the second color image are taken simultaneously at a time later than and different from a time when the first fluorescence image and the first color image are taken simultaneously;
a first region of interest setting unit which sets a region of interest at a position on the first fluorescence image;
a tissue specifying unit which specifies a position of the tissue on the first color image, the position corresponding to the position of the region of interest on the first fluorescence image;
a tissue tracing unit which creates a tissue image including the tissue based on at least one of the plurality of color images, and specifies a position of the tissue on the second color image based on the second color image and the tissue image, and calculates a vector of movement of the tissue between the first color image and the second color image based on the position of the tissue on the first color image and the position of the tissue on the second color image;
a second region of interest setting unit which sets the region of interest at a position on the second fluorescence image, wherein the position is calculated based on the position of the region of interest on the first fluorescence image and the vector of movement of the tissue, and the position corresponds to the position of the tissue on the second color image; and
a pixel value measuring unit which measures a pixel value of the region of interest.
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