	US 11,937,625 B2
	Oral administration formulation of blueberry extract as a coadjuvant for preserving the health of human precorneal film
Arturo Santos Garcia, Zapopan (MX); Juan Carlos Altamirano Vallejo, Zapopan (MX); Jose Alonso Chavez Garcia, Zapopan (MX); and Alejandro Gonzalez De La Rosa, Zapopan (MX)
Appl. No. 16/954,401
Filed by CENTRO DE RETINA MEDICA Y QUIRURGICA, S.C., Zapopan (MX)
PCT Filed Dec. 18, 2018, PCT No. PCT/MX2018/000154 § 371(c)(1), (2) Date Jun. 16, 2020, PCT Pub. No. WO2019/125127, PCT Pub. Date Jun. 27, 2019.
Claims priority of application No. MX/A/2017/016991 (MX), filed on Dec. 20, 2017.
Prior Publication US 2021/0076726 A1, Mar. 18, 2021
Int. Cl. A23L 33/19 (2016.01); A23L 33/105 (2016.01); A23L 33/12 (2016.01); A23L 33/155 (2016.01)

CPC A23L 33/19 (2016.08) [A23L 33/105 (2016.08); A23L 33/12 (2016.08); A23L 33/155 (2016.08)]

10 Claims

1. A method to improve the health of precorneal tear film of the patient in need thereof, comprising the steps of:

orally administering to the patient a food supplement formulation comprising:

a. blueberry extract;

b. eicosapentaenoic acid (EPA) omega;

c. docosahexaenoic acid (DHA) omega-3;

d. recombinant human lactoferrin covalently bound directly to one or more polyethylene glycol moieties;

e. Vitamin E;

f. Vitamin A; and

g. an excipient;

wherein said food supplement formulation is an adjuvant;

wherein said excipient is a surfactant that promotes the formation of micelles; and

wherein said food supplement formulation is encapsulated with a colloidal gel that is soft gelatin.