CPC C07K 16/40 (2013.01) [C07K 14/7051 (2013.01); C07K 2317/24 (2013.01); C07K 2317/565 (2013.01); C07K 2317/622 (2013.01); C07K 2319/03 (2013.01)] | 18 Claims |
1. An anti-human ROR1 antibody or an antigen-binding fragment thereof comprising VH having an amino acid sequence at least 90% identical to SEQ ID NO: 2 and VL having an amino acid sequence at least 90% identical to SEQ ID NO: 3, the antibody or antigen-binding fragment comprising complementarity determining regions (CDRs) in the VH and the VL, wherein a CDR1 of the VH comprises the sequence TYA, a CDR2 of the VH comprises SEO ID NO: 41, a CDR3 of the VH comprises SEO ID NO: 42, a CDR1 of the VL comprises SEQ ID NO: 43, a CDR2 of the VL comprises the sequence RAN, and a CDR3 of the VL comprises SEQ ID NO: 45.
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