US 11,931,463 B2
All-in-one fixed-dose combination for treating Helicobacter pylori infection
Reza Fathi, Oradell, NJ (US); Gilead Raday, Palo Alto, CA (US); Guy Goldberg, Tel Aviv (IL); and Patrick Gosselin, Laval (CA)
Assigned to RedHill Biopharma Ltd., Tel-Aviv (IL)
Filed by RedHill Biopharma Ltd., Tel-Aviv (IL)
Filed on Aug. 20, 2021, as Appl. No. 17/408,111.
Application 17/408,111 is a continuation of application No. 16/515,621, filed on Jul. 18, 2019, granted, now 11,135,172.
Application 16/515,621 is a continuation of application No. 16/274,634, filed on Feb. 13, 2019, granted, now 10,898,439, issued on Jan. 26, 2021.
Application 16/274,634 is a continuation of application No. 15/466,305, filed on Mar. 22, 2017, granted, now 10,238,606, issued on Mar. 26, 2019.
Application 15/466,305 is a continuation of application No. 15/135,309, filed on Apr. 21, 2016, granted, now 9,603,806, issued on Mar. 28, 2017.
Application 15/135,309 is a continuation of application No. 14/522,921, filed on Oct. 24, 2014, granted, now 9,498,445, issued on Nov. 22, 2016.
Application 14/522,921 is a continuation of application No. 14/179,197, filed on Feb. 12, 2014, granted, now 9,050,263, issued on Jun. 9, 2015.
Claims priority of provisional application 61/764,401, filed on Feb. 13, 2013.
Claims priority of provisional application 61/764,385, filed on Feb. 13, 2013.
Prior Publication US 2022/0062188 A1, Mar. 3, 2022
This patent is subject to a terminal disclaimer.
Int. Cl. A61K 9/48 (2006.01); A61K 9/50 (2006.01); A61K 31/395 (2006.01); A61K 31/43 (2006.01); A61K 31/435 (2006.01); A61K 31/438 (2006.01); A61K 31/4439 (2006.01)
CPC A61K 9/4808 (2013.01) [A61K 9/4866 (2013.01); A61K 9/4891 (2013.01); A61K 9/5026 (2013.01); A61K 9/5047 (2013.01); A61K 9/5084 (2013.01); A61K 31/395 (2013.01); A61K 31/43 (2013.01); A61K 31/435 (2013.01); A61K 31/438 (2013.01); A61K 31/4439 (2013.01)] 15 Claims
 
1. An all-in-one capsule comprising:
about 12.5 mg rifabutin;
about 250 mg amoxicillin; and
about 10 mg omeprazole,
wherein the omeprazole is in the form of a first plurality of minitablets.