US 11,926,868 B2
Immunoprobe-based method to assess organ injury status through a biofluid-based cell-free DNA (cfDNA) assay
Minnie M. Sarwal, San Francisco, CA (US); Tara K. Sigdel, San Francisco, CA (US); and Joshua Y. Yang, San Francisco, CA (US)
Assigned to The Regents of the University of California, Oakland, CA (US)
Filed by The Regents of the University of California, Oakland, CA (US)
Filed on Jul. 15, 2021, as Appl. No. 17/376,919.
Application 17/376,919 is a continuation of application No. 16/325,385, granted, now 11,124,824, previously published as PCT/US2017/047372, filed on Aug. 17, 2017.
Claims priority of provisional application 62/376,299, filed on Aug. 17, 2016.
Prior Publication US 2021/0340610 A1, Nov. 4, 2021
This patent is subject to a terminal disclaimer.
Int. Cl. C12Q 1/6876 (2018.01); C12Q 1/6813 (2018.01); C12Q 1/6827 (2018.01); C12Q 1/6853 (2018.01); C12Q 1/6883 (2018.01); G01N 33/53 (2006.01); G01N 33/68 (2006.01); G16H 10/40 (2018.01); G01N 33/70 (2006.01)
CPC C12Q 1/6853 (2013.01) [C12Q 1/6813 (2013.01); C12Q 1/6827 (2013.01); C12Q 1/6876 (2013.01); C12Q 1/6883 (2013.01); G01N 33/53 (2013.01); G01N 33/68 (2013.01); G01N 33/6827 (2013.01); G01N 33/6839 (2013.01); G16H 10/40 (2018.01); C12Q 2600/112 (2013.01); C12Q 2600/118 (2013.01); C12Q 2600/154 (2013.01); C12Q 2600/158 (2013.01); G01N 33/70 (2013.01); G01N 2800/245 (2013.01); G01N 2800/347 (2013.01)] 6 Claims
OG exemplary drawing
 
1. A nucleic acid probe for detecting an Alu nucleic acid sequence in a nucleic acid from a biofluidic sample, comprising the nucleic acid sequence of SEQ ID NO: 2 covalently linked to a detectable moiety.