CPC C07K 16/244 (2013.01) [A61K 38/1709 (2013.01); G01N 33/6869 (2013.01); A61K 2039/505 (2013.01); A61K 2039/545 (2013.01); C07K 2317/30 (2013.01); C07K 2317/76 (2013.01); C07K 2317/92 (2013.01); G01N 2333/54 (2013.01)] | 28 Claims |
1. A method for the treatment of a pediatric autoinflammatory disease or condition and/or symptoms associated with said disease or condition in a subject, said method comprising administering to said subject an IL-18 inhibitor, wherein the IL-18 inhibitor is an IL-18 binding protein (IL-18BP) or an active fragment thereof, wherein the IL-18BP or the active fragment thereof comprises N-terminal and/or C-terminal deletion variants of IL-18BP, which are present in an amount of less than 30%.
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