CPC C07F 9/2458 (2013.01) [A61K 31/404 (2013.01); A61P 35/00 (2018.01); C07C 227/14 (2013.01); C07C 245/18 (2013.01); C07C 271/22 (2013.01); C07D 209/18 (2013.01); C07D 209/20 (2013.01); C07D 211/90 (2013.01); C07D 263/04 (2013.01); C07D 263/18 (2013.01); C07D 309/10 (2013.01); C07D 317/38 (2013.01); C07D 317/40 (2013.01); C07D 473/34 (2013.01); C07F 9/65616 (2013.01); C07H 15/203 (2013.01); C07H 19/207 (2013.01); C07K 5/06026 (2013.01); C07K 5/06156 (2013.01); C07K 5/0808 (2013.01); A61K 38/00 (2013.01)] | 16 Claims |
1. A compound having formula (I):
or a pharmaceutically acceptable salt thereof, wherein:
X is —(CH2)n—, wherein n is 1;
R1 is selected from the group consisting of H, C1-6 alkyl, and substituted C1-6 alkyl;
R2 is —C(═O)—O—(CR3R4)m—O—C(═O)—R10;
R2′ is selected from the group consisting of H, C1-C6 alkyl, and substituted C1-C6 alkyl;
each R3 and R4 are independently H, C1-C6 alkyl, substituted C1-C6 alkyl, aryl,
substituted aryl or
m is 1; and
R10 is selected from the group consisting of alkyl, substituted alkyl, cycloalkyl, substituted cycloalkyl, monosaccharide, acylated monosaccharide, aryl, substituted aryl, heteroaryl, and substituted heteroaryl.
|