CPC C07D 417/14 (2013.01) | 20 Claims |
1. A compound having the formula:
or a pharmaceutically acceptable salt thereof,
wherein:
X1 is S;
Ra is selected from the group consisting of H, halogen, and C1-3 alkyl;
R1 is
R3 is H or alkyl;
R4 is selected from the group consisting of alkyl, —(SO2)alkyl, —(SO2)alkyleneheterocyclyl, —(SO2)haloalkyl, —(SO2)haloalkoxy, —(SO2)cycloalkyl, and —(SO2)N(alkyl)(R3); and
R5 is aryl; or
R4 and R5 together with the atom to which they are attached form a heterocyclyl, optionally substituted with one or more halogen, alkyl, haloalkyl, alkoxy, and haloalkoxy.
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