CPC A61N 1/36139 (2013.01) [A61N 1/0534 (2013.01); A61N 1/36082 (2013.01); A61N 1/36096 (2013.01); A61N 1/36171 (2013.01)] | 16 Claims |
1. A method comprising:
delivering, via a plurality of electrodes implanted in a brain of a patient, electrical stimulation to a stimulation site of the brain of the patient, wherein the stimulation site comprises a neural connection to a target site of the brain of the patient, and wherein the stimulation site comprises a Fornix of the brain of the patient;
sensing, via the plurality of electrodes and from the target site, bioelectrical brain activity comprising a bioelectrical response to the delivery of the electrical stimulation, the bioelectrical response overlapping in time with at least a portion of the delivery of the electrical stimulation;
detecting, by processing circuitry, a biomarker in the bioelectrical response, the biomarker occurring during the delivery of the electrical stimulation;
determining, by the processing circuitry, at least one parameter value of subsequent electrical stimulation based on the detected biomarker; and
delivering, via the plurality of electrodes, the subsequent electrical stimulation according to the determined at least one parameter value to the stimulation site to achieve a patient state in the target site.
|