US 11,925,674 B2
Methods for regulating free fatty acid flux using fat specific protein 27 (FSP27) compositions
Vishwajeet Puri, Athens, OH (US); John Kopchick, Athens, OH (US); and Vishva Sharma, Athens, OH (US)
Assigned to Ohio University, Athens, OH (US)
Filed by Ohio University, Athens, OH (US)
Filed on Jul. 26, 2022, as Appl. No. 17/873,386.
Application 17/873,386 is a division of application No. 16/620,661, granted, now 11,433,117, previously published as PCT/US2018/037443, filed on Jun. 14, 2018.
Claims priority of provisional application 62/520,015, filed on Jun. 15, 2017.
Prior Publication US 2023/0129789 A1, Apr. 27, 2023
Int. Cl. A61K 38/17 (2006.01); A61K 9/00 (2006.01); A61P 3/00 (2006.01); A61P 3/06 (2006.01); A61P 3/10 (2006.01); G01N 33/50 (2006.01)
CPC A61K 38/1709 (2013.01) [A61P 3/00 (2018.01); A61P 3/06 (2018.01); A61P 3/10 (2018.01); A61K 9/0019 (2013.01)] 2 Claims
 
1. A pharmaceutical composition comprising a nucleic acid encoding a Fat Specific Protein 27 (FSP27) sequence as an active ingredient wherein said composition exhibits a decrease in lipolysis in adipocytes in a patient; wherein the nucleic acid encoding the FSP27 sequence consists of amino acid residues at positions 120-220 of SEQ ID NO: 2, together with one or more non-naturally occurring excipients, carriers and/or diluents.