US 11,925,650 B2
Antibacterial chemical compound, its manufacturing method and its use thereof
Hao-Chieh Chiu, Taipei (TW); and Chung-Wai Shiau, Taipei (TW)
Assigned to NATIONAL TAIWAN UNIVERSITY, Taipei (TW); and NATIONAL YANG MING CHIAO TUNG UNIVERSITY, Taipei (TW)
Filed by National Taiwan University, Taipei (TW); and National Yang Ming Chiao Tung University, Taipei (TW)
Filed on Mar. 4, 2022, as Appl. No. 17/686,949.
Prior Publication US 2023/0277551 A1, Sep. 7, 2023
Int. Cl. A61K 31/5513 (2006.01); A61K 31/165 (2006.01); A61K 31/431 (2006.01); A61K 31/496 (2006.01); A61K 31/5383 (2006.01); A61K 31/65 (2006.01); A61K 31/7036 (2006.01); A61P 31/04 (2006.01); C07D 495/04 (2006.01)
CPC A61K 31/5513 (2013.01) [A61K 31/165 (2013.01); A61K 31/431 (2013.01); A61K 31/496 (2013.01); A61K 31/5383 (2013.01); A61K 31/65 (2013.01); A61K 31/7036 (2013.01); A61P 31/04 (2018.01); C07D 495/04 (2013.01)] 13 Claims
 
1. A compound (I) having following structure:

OG Complex Work Unit Chemistry
or a pharmaceutically acceptable salt thereof,
wherein
X1 is O;
X2 is CH;
X3 is CHCH;
R1 is H, CH3 or Cl; and
R2 is

OG Complex Work Unit Chemistry