US 11,913,076 B2
Prostate cancer gene profiles and methods of using the same
Shiv K. Srivastava, Potomac, MD (US); Gyorgy Petrovics, Bethesda, MD (US); and Indu Kohaar, North Potomac, MD (US)
Assigned to THE HENRY M. JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY MEDICINE, INC., Bethesda, MD (US)
Appl. No. 16/611,692
Filed by THE HENRY M. JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY MEDICINE, INC., Bethesda, MD (US)
PCT Filed May 8, 2018, PCT No. PCT/US2018/031550
§ 371(c)(1), (2) Date Nov. 7, 2019,
PCT Pub. No. WO2018/208749, PCT Pub. Date Nov. 15, 2018.
Claims priority of provisional application 62/505,798, filed on May 12, 2017.
Prior Publication US 2021/0108271 A1, Apr. 15, 2021
Int. Cl. C12Q 1/68 (2018.01); C07H 21/04 (2006.01); C12Q 1/6886 (2018.01); G16B 25/20 (2019.01); G16B 25/10 (2019.01)
CPC C12Q 1/6886 (2013.01) [G16B 25/10 (2019.02); G16B 25/20 (2019.02); C12Q 2600/158 (2013.01)] 5 Claims
OG exemplary drawing
 
1. A method of obtaining a gene expression profile in a biological sample from a patient, the method comprising:
detecting expression of a plurality of genes in a biological sample obtained from the patient, wherein the plurality of genes consists of PCA3, PCGEM1, and optionally a control gene, and wherein the biological sample comprises exosomes or nucleic acids isolated from exosomes obtained from a non-DRE urine sample.