CPC C12M 25/14 (2013.01) [C12M 23/40 (2013.01); C12M 41/44 (2013.01)] | 23 Claims |
1. A bioreactor, comprising:
a scaffold seeded with a plurality of cells and having an extended state and a non-extended state;
a scaffold support that selectively modifies a state of the scaffold from the non-extended state to the extended state; and
a manifold configured to provide a medium to the scaffold, wherein the scaffold support modifies the state of the scaffold from the non-extended state to the extended state at a rate tuned to maintain a cell density associated with the plurality of cells within a particular density range.
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