US 11,912,972 B2
Scaffold bioreactor
Zheng Huang, Bolton, MA (US); Natalie Rose Rubio, Malden, MA (US); and Orianna Elysse Kane, Boston, MA (US)
Assigned to Ark Biotech Inc., Westwood, MA (US)
Filed by Ark Biotech Inc., Westwood, MA (US)
Filed on Mar. 30, 2023, as Appl. No. 18/128,772.
Claims priority of provisional application 63/334,412, filed on Apr. 25, 2022.
Prior Publication US 2023/0340388 A1, Oct. 26, 2023
Int. Cl. C12M 1/12 (2006.01); C12M 1/34 (2006.01); C12M 1/26 (2006.01); C12M 3/00 (2006.01); C12M 1/00 (2006.01)
CPC C12M 25/14 (2013.01) [C12M 23/04 (2013.01); C12M 23/40 (2013.01); C12M 23/44 (2013.01); C12M 23/48 (2013.01); C12M 33/04 (2013.01); C12M 41/34 (2013.01)] 17 Claims
OG exemplary drawing
 
1. A system for culturing cells, comprising:
a bioreactor including a scaffold on which the cells tend to adhere and a tray that supports the scaffold, wherein the tray includes an array of rods and the scaffold is woven in-between the array of rods; and
a circulatory system that intermittently flows fluid over the scaffold, wherein the circulatory system includes:
a media recirculation tank that includes the fluid; and
a pump that causes the fluid to flow from the media recirculation tank to the scaffold, wherein the pump is turned on and turned off during a batch of culturing the cells to enable the fluid to intermittently flow over the scaffold.