CPC C07D 471/14 (2013.01) [A61K 31/437 (2013.01); A61K 31/438 (2013.01); A61K 31/4375 (2013.01); A61K 45/06 (2013.01); A61P 25/00 (2018.01); C07D 471/20 (2013.01)] | 11 Claims |
1. A compound having the structure:
wherein
X is N or NH;
R1 is —OH, —O-alkyl, —O(CO)-alkyl or is absent;
R2 is —H or -alkyl;
R3 is —H or -alkyl;
R4 is —H or -alkyl;
α is a bond and is absent or present;
β is a bond and is absent or present; and
χ is a bond and is absent or present,
wherein when α is absent, β is present, χ is absent, X is NH and R1 is absent, and
wherein when α is present, β is absent, χ is present, X is N and R1 is present,
or a pharmaceutically acceptable salt or ester thereof.
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