CPC A61K 39/125 (2013.01) [A61K 39/12 (2013.01); A61K 39/13 (2013.01); A61K 39/39 (2013.01); C07K 16/1009 (2013.01); A61K 2039/505 (2013.01); A61K 2039/5252 (2013.01); A61K 2039/5258 (2013.01); A61K 2039/53 (2013.01); A61K 2039/55 (2013.01); A61K 2039/58 (2013.01); C12N 2770/32334 (2013.01)] | 21 Claims |
1. A method of inducing an immune response to coxsackie B virus (CBV) in a pregnant woman, the method comprising administering to the pregnant woman an effective amount of a composition comprising:
a) a nucleic acid encoding a protein or peptide comprising a viral antigenic epitope of CBV1 and a nucleic acid encoding a protein or peptide comprising a viral antigenic epitope of CBV2; and
b) at least one nucleic acid selected from a nucleic acid encoding a protein or peptide comprising a viral antigenic epitope of CBV3, a nucleic acid encoding a protein or peptide comprising a viral antigenic epitope of CBV4, and a nucleic acid encoding a protein or peptide comprising a viral antigenic epitope of CBV5, wherein the composition does not include a nucleic acid encoding a protein or peptide comprising a viral antigenic epitope of CBV6,
wherein said administering induces an immune response to CBV in the pregnant woman.
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