US 11,911,430 B2
Composition for stress relief containing fermented ripened noni and calamansi extract as active ingredients
Im Joung La, Gongju-si (KR); Geum Su Seong, Gimpo-si (KR); Eun Young Park, Gimpo-si (KR); Yong Deok Kim, Gimpo-si (KR); Eun Min Kim, Gimpo-si (KR); and Soo Jin Kim, Gimpo-si (KR)
Assigned to ATOMY OROT CO., LTD., Gongju-si (KR); and NSTBIO CO., LTD., Gimpo-si (KR)
Filed by ATOMY OROT CO., LTD., Gongju-si (KR); and NSTBIO CO., LTD., Gimpo-si (KR)
Filed on Dec. 29, 2021, as Appl. No. 17/646,467.
Claims priority of application No. 10-2020-0185599 (KR), filed on Dec. 29, 2020; and application No. 10-2021-0166914 (KR), filed on Nov. 29, 2021.
Prior Publication US 2022/0202893 A1, Jun. 30, 2022
Int. Cl. A61K 36/746 (2006.01); A61K 36/752 (2006.01); A23L 33/105 (2016.01); A23L 29/00 (2016.01); A61P 25/22 (2006.01)
CPC A61K 36/746 (2013.01) [A23L 29/065 (2016.08); A23L 33/105 (2016.08); A61K 36/752 (2013.01); A61P 25/22 (2018.01)] 4 Claims
 
1. A method for producing a composition containing fermented and aged noni or an extract thereof and a calamansi extract, the method comprising steps of:
(a) obtaining fermented and aged noni by fermenting and aging noni using lactic acid bacteria in a fermentation broth;
(b) pulverizing and squeezing frozen calamansi to yield a calamansi extract or adding water to a dried calamansi at an amount of 10-fold relative to the dried calamansi at 50° C. for 8 hours to yield a calamansi extract;
(c) filtering the calamansi extract to yield a filtered calamansi extract; and
(d) adding the filtered calamansi extract to the fermented and aged noni, followed by aging,
and wherein the fermented and aged noni is aged at 35 to 40° C. for 48 to 168 hours by pouring the fermentation broth over the fermented and aged noni.