CPC G01N 27/403 (2013.01) [A61B 5/1495 (2013.01); A61B 5/14532 (2013.01); A61B 5/14865 (2013.01)] | 21 Claims |
1. A device for continuous in vivo measurement of glucose concentrations in a host, comprising:
a first electrode;
a second electrode;
a first membrane located over at least a portion of the first electrode, the first membrane comprising an enzyme configured to catalyze a reaction of glucose and oxygen from a biological fluid in contact with the first membrane in vivo, the first membrane having a first temperature coefficient;
a second membrane located over at least a portion of the second electrode, the second membrane having a second temperature coefficient different than the first temperature coefficient; and
electronic circuitry operatively connected to the first electrode and to the second electrode, the electronic circuitry being configured to generate a signal representative of a concentration of glucose in the host and configured to measure at least one of an in vivo temperature or a change in temperature in vivo, the measuring using the first membrane and the second membrane.
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