US 11,891,650 B2
Fluid cartridge with valve mechanism
David Eberhart, Santa Clara, CA (US); William D. Nielsen, San Jose, CA (US); Helen Franklin, Santa Clara, CA (US); Stevan B. Jovanovich, Livermore, CA (US); Dennis Lehto, Santa Clara, CA (US); Kaiwan Chear, Livermore, CA (US); James Klevenberg, Livermore, CA (US); Chungsoo Charles Park, Fremont, CA (US); Corey M. Smith, Los Altos, CA (US); Philip Justus Wunderle, Oakland, CA (US); and David King, Menlo Park, CA (US)
Assigned to INTEGENX, INC., Pleasanton, CA (US)
Filed by INTEGENX, INC., Pleasanton, CA (US)
Filed on Feb. 22, 2021, as Appl. No. 17/181,228.
Application 17/181,228 is a division of application No. 16/250,646, filed on Jan. 17, 2019, granted, now 10,961,561.
Application 16/250,646 is a division of application No. 15/117,053, granted, now 10,208,332, previously published as PCT/US2015/028510, filed on Apr. 30, 2015.
Claims priority of provisional application 62/069,752, filed on Oct. 28, 2014.
Claims priority of provisional application 62/069,473, filed on Oct. 28, 2014.
Claims priority of provisional application 62/067,404, filed on Oct. 22, 2014.
Claims priority of provisional application 62/067,120, filed on Oct. 22, 2014.
Claims priority of provisional application 62/067,429, filed on Oct. 22, 2014.
Claims priority of provisional application 62/001,533, filed on May 21, 2014.
Prior Publication US 2021/0180114 A1, Jun. 17, 2021
Int. Cl. C12Q 1/6806 (2018.01); B01L 3/00 (2006.01); C12Q 1/686 (2018.01); G01N 27/447 (2006.01)
CPC C12Q 1/6806 (2013.01) [B01L 3/50273 (2013.01); B01L 3/502707 (2013.01); B01L 3/502715 (2013.01); B01L 3/502738 (2013.01); C12Q 1/686 (2013.01); G01N 27/44743 (2013.01); G01N 27/44791 (2013.01); B01L 2200/027 (2013.01); B01L 2200/0689 (2013.01); B01L 2200/12 (2013.01); B01L 2300/041 (2013.01); B01L 2300/0654 (2013.01); B01L 2300/0681 (2013.01); B01L 2300/087 (2013.01); B01L 2300/0848 (2013.01); B01L 2300/123 (2013.01); B01L 2400/0406 (2013.01); B01L 2400/0478 (2013.01)] 19 Claims
OG exemplary drawing
 
1. An article comprising:
(a) a body comprising a malleable and plastically deformable material and comprising:
(i) a surface,
(ii) one or more channels formed in the surface, and
(iii) one or more valve bodies formed in the surface and in fluidic communication with the one or more channels, respectively, the one or more valve bodies comprising:
(A) a segment of a respective channel of the one or more channels, the segment comprising a wall having a pair of ridges raised above the surface and a floor depressed into the surface; and
(B) reliefs depressed into the surface and defining depressions that flank the ridges on two sides of the segment.