US 11,891,628 B2
Method for biomimetic culture of urothelial cells and uses thereof
Chih-Rong Shyr, Taichung (TW); Chi-Ping Huang, Taichung (TW); and Chun-Chie Wu, Taichung (TW)
Assigned to China Medical University, Taichung (CN)
Appl. No. 17/053,667
Filed by China Medical University, Taichung (TW)
PCT Filed May 14, 2019, PCT No. PCT/CN2019/086782
§ 371(c)(1), (2) Date Nov. 6, 2020,
PCT Pub. No. WO2019/218995, PCT Pub. Date Nov. 21, 2019.
Claims priority of provisional application 62/671,404, filed on May 14, 2018.
Prior Publication US 2021/0095255 A1, Apr. 1, 2021
Int. Cl. A61K 35/22 (2015.01); C12N 5/071 (2010.01); A61P 13/10 (2006.01); A61P 35/00 (2006.01); A61K 9/00 (2006.01); A61K 45/06 (2006.01)
CPC C12N 5/0685 (2013.01) [A61K 9/0034 (2013.01); A61K 35/22 (2013.01); A61P 13/10 (2018.01); A61P 35/00 (2018.01); A61K 45/06 (2013.01)] 5 Claims
 
1. A method for treating a subject suffering from urothelial carcinoma, or bladder cancer, comprising administering intravesically to the subject an effective amount of a composition comprising xenogeneic urothelial cells in a solution wherein the xenogeneic urothelial cells are urothelial stem cells, urothelial progenitor cells, urothelial precursor cells and mature urothelial cells.