	US 11,890,322 B2
	Methods for promoting wound healing and hair growth comprising GDNF administration
Robert E. Braun, Bar Harbor, ME (US); and Manju Sharma, Bar Harbor, ME (US)
Assigned to The Jackson Laboratory, Bar Harbor, ME (US)
Filed by The Jackson Laboratory, Bar Harbor, ME (US)
Filed on Jul. 13, 2021, as Appl. No. 17/373,877.
Application 16/452,459 is a division of application No. 14/775,386, granted, now 10,376,562, previously published as PCT/US2014/027419, filed on Mar. 14, 2014.
Application 17/373,877 is a continuation of application No. 16/452,459, filed on Jun. 25, 2019, abandoned.
Claims priority of provisional application 61/787,870, filed on Mar. 15, 2013.
Prior Publication US 2022/0062381 A1, Mar. 3, 2022
This patent is subject to a terminal disclaimer.
Int. Cl. A61K 38/18 (2006.01); C07K 14/475 (2006.01); A61K 8/64 (2006.01); A61Q 7/00 (2006.01)

CPC A61K 38/185 (2013.01) [A61K 8/64 (2013.01); A61Q 7/00 (2013.01); C07K 14/4756 (2013.01)]

18 Claims

1. A method for promoting hair growth comprising:

administering to skin comprising hair follicles of a subject in need thereof a therapeutically effective dose of a topical formulation comprising recombinant human glial cell-derived neurotrophic factor (GDNF),

wherein the therapeutically effective dose is 1-10 mg, 10-20 mg, 20-30 mg, or 30-40 mg, thereby promoting an increase in hair follicle number of the skin of the subject.