	US 11,890,316 B2
	Oral octreotide therapy and contraceptive methods
Asi Haviv, Gan-Shlomo (IL); Ruth Engle Stevens, Long Beach, WA (US); and Jennings Ray Dawkins, Coats, NC (US)
Assigned to Amryt Endo, Inc., Boston, MA (US)
Filed by Amryt Endo, Inc., Boston, MA (US)
Filed on Sep. 9, 2021, as Appl. No. 17/470,836.
Application 17/470,836 is a continuation of application No. 17/135,328, filed on Dec. 28, 2020, granted, now 11,141,457.
Prior Publication US 2022/0233633 A1, Jul. 28, 2022
This patent is subject to a terminal disclaimer.
Int. Cl. A61K 38/12 (2006.01); A61K 9/00 (2006.01)

CPC A61K 38/12 (2013.01) [A61K 9/0053 (2013.01)]

26 Claims

1. A method of administering oral octreotide to a female subject in need thereof wherein the subject is in need of a contraceptive method, comprising

(a) administering to the subject an oral dosage form comprising:

a composition comprising a suspension which comprises an admixture of a hydrophobic medium and a solid form,

wherein the solid form comprises a therapeutically effective amount of octreotide and a medium chain fatty acid salt, wherein the composition comprises 12% to 21% by weight of the medium chain fatty acid salt; and

(b) counseling the subject to avoid concomitant use of a combined oral contraceptive.