CPC A61K 35/17 (2013.01) [A01K 67/0271 (2013.01); A61K 9/0024 (2013.01); A61K 9/146 (2013.01); A61K 39/44 (2013.01); A61K 45/06 (2013.01); C07K 16/2809 (2013.01); C07K 16/2818 (2013.01); C07K 16/2878 (2013.01); C12N 5/0694 (2013.01); A01K 2207/12 (2013.01); A01K 2227/105 (2013.01); A01K 2267/0331 (2013.01); C12N 2510/00 (2013.01); C12N 2533/54 (2013.01); C12N 2533/74 (2013.01)] | 19 Claims |
1. An ex vivo implantable composition comprising (i) a porous scaffold comprising pores; (ii) tumor reactive lymphocytes within the pores; and (iii) at least one antibody selected from an anti-CD3 antibody, an anti-CD28 antibody, and an anti-CD137 antibody.
|