CPC A61B 90/08 (2016.02) [A61L 31/04 (2013.01); A61L 31/12 (2013.01); A61L 31/128 (2013.01); A61L 31/14 (2013.01); A61L 31/146 (2013.01); A61B 2090/0816 (2016.02); A61L 2420/08 (2013.01)] | 9 Claims |
1. A method for preventing an adhesion, comprising applying a sterilized biocompatible sponge-like laminate that includes first and second sponge-like layers containing low-endotoxin monovalent metal salts of alginic acid which are at least partially crosslinked with a curing agent, wherein a weight average molecular weight of the monovalent metal salt of alginic acid in the first layer is 10,000-2,000,000, a weight average molecular weight of the monovalent metal salt of alginic acid in the second layer is 1,000-1,000,000, the weight average molecular weights are measured by GPC-MALS method following a decrosslinking treatment, and the weight average molecular weight of the monovalent metal salt of alginic acid in the first layer is higher than the weight average molecular weight of the monovalent metal salt of alginic acid in the second layer, to a subject in need of adhesion prevention.
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